A fluorescent molecular ruler as a selective probe for ω-aminoacids.
نویسندگان
چکیده
A fluorescent probe for ω-aminoacids behaves as a molecular ruler, changing the yellow fluorescent emission into blue as a function of the distance between the terminal ammonium and the carboxylate groups, permitting the quantitative detection of ω-aminoacids, their metabolites and related drugs, such as pregabalin or gabapentin, from pharmaceutical formulations.
منابع مشابه
An amine/imine functionalized microporous MOF as a new fluorescent probe exhibiting selective sensing of Fe3+ and Al3+ over mixed metal ions
Nowadays metal-organic frameworks with multiple luminescent centers are very fascinating as multifunctional luminescent material because of their luminescence properties, which could be systematically tuned by deliberate use of organic ligands and metal ions. In this research, we explored a microporous mixed-ligand MOF for highly selective and sensitive detection of metal ions. A two-fold inter...
متن کاملDesign of a Fluorescent Sensor Based on the Polydopamine Nanoparticles for Detection of Gallic Acid
Background: Gallic acid (GA) is one of the polyphenolic compounds with antioxidant, antimicrobial and radical scavenging activities, which plays a main role in human health against cancer and cardiovascular diseases. GA concentration can be quantitatively measured in food, medicinal plants and body fluids. Materials and Methods: In this study, MnO2 nanosheets were prepared by reducing potassium...
متن کاملP-11: DHR123: A Suitable Fluorescent Mitochondrial Probe for Assessment of H2O2 in Human Spermatozoa
Background: The objective of present study was to assess potential of DHR123 (dihydrorhodamine 123) fluorescent probe for measurement of H2O2 produced by human spermatozoa and comparing the results with DCFH-DA (2', 7'-dichlorodihydrofluorescein diacetate). Materials and Methods: Fluorescent intensity and percentage R123 and DCF positive sperm measured by flow cytometry. The suitable ...
متن کاملEvaluation and Characterization of Free and Immobilized Acethylcholinesterase with Fluorescent Probe, Differential Scanning Calorimetry and Docking
Acetylcholinesterase (AChE) enzyme which catalyses the hydrolysis of choline esters, such as acetylcholine, is very important in nerve function. Previous structural studies showed the possible amyloid fibril formation on the AChE. Therefore it is important to understand interaction of ligands to prevent the formation of amyloid fibrils. The purpose of the present study was to char...
متن کاملParameters of ZnS/Metal/ZnS nanostructured systems with different metal layers
ZnS/metal/ZnS (ZMZ) nanomultilayer films with Au, Ag and Cu as a metal layer have been deposited on a glass substrate by thermal evaporation and then, were annealed in air at different temperatures from 100 to 300 ºC for one hour. Several analytical tools such as X-ray diffraction, four point probe and spectrophotometer were used to study the changes in structural, electrical and optical proper...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Chemical communications
دوره 47 11 شماره
صفحات -
تاریخ انتشار 2011